jop kind hubrecht institute

Hubrecht Institute, NL. We are interested in how cells acquire new identities and traits in lineage specification events in mice and in cancer. Read more | 11 November . Hubrecht Institute opens new laboratory building. Cited by. Contact. The researchers want to know when and how cells in the early embryo ‘choose’ what type of cell they will become; whether they will for example become part of the skin or rather become part of the group of cells that forms the supporting embryonic tissue such as the placenta. This type of DNA damage can have an endogenous cause, but it can also be caused by external influences, such as high dosages of chemotherapy in cancer. She and others previously discovered that the Fanconi anemia (FA) pathway plays a crucial role in repairing ICLs. Biography. Verified email at hubrecht.eu. Jobs. About. EMBL alumnus Jop Kind’s research focuses on the role of DNA organisation in genome stability, cell development and disease. Jop Kind. 3584 CT Utrecht Molecular mechanisms and regulation of DNA repair; Hubrecht Institute . Credit: Jop Kind, copyright Hubrecht Institute. PMID: 31118510 PMCID: PMC6546605 Articles Cited by. Afterwards, Alexander van Oudenaarden, Mauro Muraro and Waleed Kholosy will also give talks and elaborate on some specific applications and usage of single cell technology. Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. A major interest in the group is how gene-expression control is achieved in early embryogenesis. Additionally, they study how new cell types arise in the early development of mouse embryos, in which epigenetics plays an important role. j.kind@hubrecht.eu. As a postdoctoral fellow in the lab of Bas van Steensel at the NKI, Jop developed novel techniques to visualize and profile single-cell spatial genome organization. Jop Kind, group leader at the Hubrecht Institute, has been awarded the John Kendrew award. Jop, now Group Leader at … 12:35. Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Annual Scientific Meeting. Isabel Guerreiro 1 , Jop Kind 2 Affiliations 1 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. The John Kendrew Young Scientist Award (JKA) was launched in 2007 as an initiative from the EMBL Pensioner’s Association to honour EMBL’s first Director General, Sir John Kendrew (1975-1982), and to support scientists in the early stages of their career. Verified account Protected Tweets @; Suggested users An ICL occurs when the two strands of our DNA are connected unnaturally. Together with her group, Knipscheer studies the repair pathways that cells use to correct ICLs. Geert Kops Group. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Title. Jop Kind, group leader at the Hubrecht Institute, has been awarded a NWO Vidi-grant. We use this approach to understand how gene-expression is controlled and to obtain insight into the regulatory mechanisms that govern cellular decision making in mouse early embryogenesis. Friends raise €290.800,- for Hubrecht Institute. To obtain detailed insight into this trajectory, it is essential to capture all the stages with single-cell accuracy. Spatiotemporal regulation of genomic function; Hubrecht Institute. Jop Kind The organization of DNA within the eukaryotic nucleus is important for cellular processes such as regulation of gene expression and repair of DNA damage. Annual Scientific Meeting. Key words: Single-cell genomics, epigenetics, spatial genome organization, bioinformatics, gene-regulation, embryogenesis, tumorigenesis. KIT, Royal Tropical Institute. The Kind group researches gene regulation – how genes are turned on or off – and the influence of the packing of DNA, the epigenetics, on this mechanism. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). Jop, now Group Leader at … Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on … Puck Knipscheer is group leader at the Hubrecht Institute and Oncode investigator. Go to Website Navigation: Home; about narcis; login; Nederlands; contact. The grant was awarded to only 327 out of 2506 applicants. Duplicate citations. Seeing is sequencing: linking phenotypes and genotypes of heterogeneous cancer cells by high-throughput, microscopy-based single cell selection and functionally annotated single cell sequencing. Despite extensive research into the molecular pathways that sense and repair DNA double-strand breaks (DSBs), comparatively little is known about management of breaks within different genomic and chromatin contexts. Jop Kind, Junior Group Leader at the Hubrecht Institute. Genome instability; UMC Utrecht. Cell division & chromosome segregation; Hubrecht Institute. Scientists from the groups of Puck Knipscheer (Hubrecht Institute) and Ketan J. Patel (MRC Laboratory of Molecular Biology) studied the second line of … To this end we employ and continuously develop novel single-cell technologies to delineate these processes with high sensitivity and accuracy. An important contributor to the regulation of gene expression is the spatial positioning of genes within the 3-dimensional space of the nucleus. Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ Online event. That way, we hope to better understand the relationship between epigenetics and the emergence of new cell types”, says Kind. PhD. Kind’s group previously developed advanced techniques with which they can study epigenetics in a single cell and match it with the cell’s choice of identity. Get Funding: Convey the impact of your scientific vision. 13:35. Hubrecht Institute. More information. Cell-fate decisions and the role of epigenetics in DNA double-strand repair In particular, the group is interested in developing high-resolution single-cell techniques which can trace dynamic chromatin changes in living cells. Contact. Sort. This is particularly difficult to study because DSBs occur randomly in the genome, thus every single cell harbors a different DSB-landscape. To study DSB-repair in single cells, we have adapted scDam&T to generate maps of DSB-repair sites in single cells. That knowledge underlines the link between alcohol consumption and cancer. Kim L de Luca 1 , Jop Kind 2 ... 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. Jop Kind, Junior Group Leader at the Hubrecht Institute. Hubrecht Institute launches new website! Protein–DNA interactions are essential for establishing cell type–specific chromatin architecture and gene expression. Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. Sara is now working as a computational biologist in the lab of Jop Kind at the Hubrecht Institute (Netherlands). Uppsalalaan 8 Self-organization in embryology. To be announced. KIT, Royal Tropical Institute. He made visible how 6 feet of DNA is dispersed in a cell nucleus of 10 micrometres. hubrecht.eu. Miao-Ping Chien. Follow. Merged citations. This method enables linking transcriptional variability to epigenetic heterogeneity. We use this approach to understand how gene-expression is controlled and to obtain insight into the regulatory mechanisms that govern cellular decision making in mouse early embryogenesis. Publications. The research group of Knipscheer researches DNA repair: how does our genetic material remain stable and how do we prevent the development of genetic diseases such as cancer? Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to map chromatin domains in single cells. ERC-starting grant for Marvin Tanenbaum and Jop Kind Marvin Tanenbaum and Jop Kind, both group leader at the Hubrecht Institute, are awarded an ERC-starting grant. We employ our single-cell genomic methods to study cellular trajectories on route towards malignant metastatic identities. Jop Kind Group. Technology development Currently, there are more than 70 PhD students at the Hubrecht Institute. Save the date! Mechanisms underlying cell-fate choice in early embryogenesis This is particularly difficult to study because DSBs occur randomly in the genome, thus every single cell harbors a different DSB-landscape. We are particularly interested in understanding the role of epigenetics and spatial genome organization in this process. Hubrecht Institute, NL. ERC-starting grant for Marvin Tanenbaum and Jop Kind. In addition, scDam&T allows determining cellular identity of cells in complex tissues -such as embryos or tumors- based on transcriptomics, in direct relation to their epigenetic regulatory landscapes (DamID). 13:05. We have developed scDam&T, a method to simultaneously capture protein-DNA interactions and transcriptomes in the same cell (Rooijers et al, 2019, Nature Biotechnology) (Figure 1). ‪Hubrecht Institute‬ - ‪Cited by 3,964‬ - ‪Single cell epigenomics‬ Citations per year. We are employing scDam&T to obtain a better understanding of the epigenetic mechanisms underlying lineage decisions in early embryogenesis, to identify the epigenetic trajectories of single cells that acquire malignant identities in tumorigenesis and to obtain insight into the role of chromatin in DNA double-strand repair. Jobs. The grant allows her to expand her group with 4 researchers for the duration of 5 years. Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on the imaginative questions that led him to the prize . 3,331. Jop Kind lab. PHOTO: EMBL . Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to map chromatin domains in single cells. Kim L de Luca 1 , Jop Kind 2 Affiliations 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. Molecular mechanisms and regulation of DNA repair; Hubrecht Institute. j.kind@hubrecht.eu. Additionally, they will investigate whether there are other, currently unknown pathways involved in repairing ICLs. Save the date for our Annual Conference! He will zoom in on single-cell epigenomics and multi-omics. PMID: 32350457 DOI: 10.1038/s41596-020-0314-8 Puck Knipscheer Group. Visit Kind's page. These topic labels come from the works of this person. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. * Correspondence: j.kind@hubrecht.eu † These authors contributed equally to this work. Network. Fingerprint. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, The Netherlands; s.lochs@hubrecht.eu (S.J.A.L. Over 17 years of experience in Molecular Biology, Yuva completed her MSc. Jop Kind is group leader at the Hubrecht Institute and Oncode Investigator. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. 13:05. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. The researchers are each given two million euros to strengthen their research groups and continue their innovative research in the next 5 years. Reads . This is harmful because it prevents the DNA from replicating and thereby makes it impossible for cells to divide. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. 13:05. Projects 1. j.kind@hubrecht.eu. Jop Kind. Partnership Agreement for Pontiac School District - Free download as PDF File (.pdf) or read online for free. His group is focused on understanding how spatial and temporal changes in genome architecture affect gene expression. 3584 CT Utrecht Read the new partnership agreement between Pontiac School District and the state including exhibits of data on the schools achievement gaps. Because DamID-signals are stable and can be carried-over for multiple generations, we are also looking into ways to exploit this property of DamID to study DSB-repair in the context of cellular decision making. Puck Knipscheer Group. 23. Network. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. The researchers in Kind’s group will use the ERC grant to further research when and how cells make these identity choices. Publications 23. Articles … Tanenbaum: Single molecule observation and manipulation of gene expression dynamics … Accurate repair of DNA damage is critical for the maintenance of genomic integrity. Miao-Ping Chien. … Jop Kind is group leader at the Hubrecht Institute and Oncode investigator. 3 Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany. Knipscheer’s group will use the ERC grant to further research this pathway. Verified email at imba.oeaw.ac.at - Homepage. ). Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to … ). Electronic address: j.kind@hubrecht.eu. By Jop Kind, Hubrecht Institute. Additionally, they are planning to build so-called molecular time machines: by giving cells a mark in the earliest stages of embryonic development, the researchers can – once the cell has made its choice – trace the epigenetic status of the cells during the earlier stages of development. Bob Roberts 2020-04-16 23:48:49? The ERC-starting grants are awarded to support up-and-coming research leaders who have recently established their own research team in Europe. We profiled these genome-lamina interactions in single cells to obtain better understanding in gene-regulation control in pre- and post-implantation embryos (Borsos et al., 2019, Nature) (. The European Research Council (ERC) awards grants to individual scientists of all nationalities and ages who perform groundbreaking research. Jop is currently an associate professor at the Hubrecht Institute in Utrecht where his lab continues to develop new techniques to single-cell profile gene-regulation to obtain better insights into the mechanisms that govern cell fate choice in development and disease. 1 Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany. Hubrecht Institute Summary: ... but instead attached to the ceiling at anchor points," says Jop Kind, group leader at the Hubrecht Institute. Here For You During COVID-19 NEW! The early mammalian conceptus (blastocyst) contains two supporting extraembryonic tissues - the trophectoderm and the primitive endoderm (PrE) - that encase and guide the epiblast (Epi) to eventually form the all body. About. Wouter de Laat Group. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Hubrecht Institute, NL. Year; Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Seeing is sequencing: linking phenotypes and genotypes of heterogeneous cancer cells by high-throughput, microscopy-based single cell selection and functionally annotated single cell sequencing. Isabel Guerreiro 1 , Jop Kind 2 Affiliations 1 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Jobs; Jobs Tips; 11 Recession-Proof Jobs; How to Get a Job; The Perfect Resume Looks Like This; How to Write A Cover Letter; 9 Attention-Grabbing Cover Letter Examples; New On Glassdoor; Best Cities for Jobs 2020; Company Reviews . Salaries, reviews and more - all posted by employees working at Hubrecht Institute. Because DamID-signals are stable and can be carried-over for multiple generations, we are also looking into ways to exploit this property of DamID to study DSB-repair in the context of cellular decision making. Jop Kind Group Jop Kind Oncode Investigator at Hubrecht Institute My Research. 3 day event 20 - 22 Jan. Masterclass: Artificial intelligence and deep learning in basic research and clinical practice in Oncology: In-depth sessions. Uppsalalaan 8 The Kind group uses a combination of single-cell genomics and microscopy methods to study the role of chromatin and epigenetics in gene-regulation control, with a focus on early mouse embryonic development and tumorigenesis. Further, in the same cells, we also profile genome-wide chromatin states with a chromatin immunocleavage (ChIC) approach to study the relationships between DSB-repair and the local chromatin environment (Figure 3). Jop Kind EMBL: Predoc, Akhtar group, Genome Biology, 2002-2008. Susanne Lens Group. Mechanisms underlying cell-fate choice in early embryogenesis A major interest in the group is how gene-expression control is achieved in early embryogenesis. Maria-Elena Torres-Padilla is group leader and director of the Institute of Epigenetics and Stem Cells (IES), Helmholtz Center Munich and professor of Stem cell biology at the Ludwig-Maximilians University. Geert Kops Group. Job Corps is the largest Free residential education and job training program for young adults ages 16–24.. We connect you with the skills and education you need to get the career you want! Accurate repair of DNA damage is critical for the maintenance of genomic integrity. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. To study DSB-repair in single cells, we have adapted scDam&T to generate maps of DSB-repair sites in single cells. We profiled these genome-lamina interactions in single cells to obtain better understanding in gene-regulation control in pre- and post-implantation embryos (Borsos et al., 2019, Nature) (Figure 2). Electronic address: j.kind@hubrecht.eu. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park. The Consolidator Grant is specifically awarded to researchers who have formed their own research group relatively recently and aim to further strengthen it further. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research . Royal Netherlands Academy of Arts & Sciences (KNAW), Hubrecht Institute; 2015 2020. j.kind@hubrecht.eu. An important contributor to the regulation of gene expression is the spatial positioning of genes within the 3-dimensional space of the nucleus. The institute encompasses 23 research groups that perform fundamental, multidisciplinary research on healthy and diseased cells, tissues and organisms. hubrecht.eu. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research. Nicolas Rivron. Silke J. About. “Our overarching goal is to further research current pathways and discover new ones in order to better understand how cells repair this type of DNA damage”, says Knipscheer. Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute, A major interest in the group is how gene-expression control is achieved in early embryogenesis. Recently, however, her group also discovered a new pathway that is involved in ICL repair; they aim to further study this newly found DNA repair route. Institute of Molecular Biotechnology, Austrian academy of science. https://lnkd.in/ekB-EJy #outsmartingcancer Hubrecht Institute, Developmental Biology and Stem Cell Research Knipscheer and Kind receive prestigious ERC Consolidator grant hubrecht.eu Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. Jop Kind lab. The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Publications 23. Spatiotemporal regulation of genomic function; Hubrecht Institute. Contact Information Mariëlle Harlé Other Events. (Jop) Kind: Active at: The Netherlands Cancer Institute: Hubrecht Institute for Developmental Biology and Stem Cell Research: Email address: If you have any questions or problems regarding login, please contact narcis@dans.knaw.nl. To be announced. Salaries, reviews, and more - all posted by employees working at Hubrecht Institute. Jop Kind, Junior Group Leader at the Hubrecht Institute. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). 23. Furthermore, as we consider technology development a core business of the group, we are continuously exploring ways to obtain richer single-cell datasets. Since October 2014 he is Junior Group Leader at the Hubrecht Institute. In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. Their combined citations are counted only for the first article. PhD. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. Hubrecht Institute. Oncode Investigator at Hubrecht Institute My Research Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. Read more | 18 November . The following articles are merged in Scholar. Jop Kind. About the Hubrecht Institute Wednesday 22 July. Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. Read more | 5 November . To achieve this, we make use of organoid and mouse models that capture tumorigenesis all the way from the initiating stages towards metastasis. Publications. Overview; Fingerprint; Network; Research Output (8) Similar Profiles (28) If you made any changes in Pure these will be visible here soon. In this conversation. Oncode, starting from a deeper understanding of the basics of cancer, works to come up with better treatments and improved diagnostics. torres-padilla@helmholtz-muenchen.de. Genomic regions contacting the NL are lamina associated domains (LADs), which contain thousands of genes that are lowl … About. Jop Kind obtained his PhD from the Radboud University in Nijmegen for his work on dosage compensation in the lab of Asifa Akhtar at the EMBL Heidelberg. Past events. Wouter de Laat Group. jop kind. EMBL alumnus Jop Kind’s research focuses on the role of DNA organisation in genome stability, cell development and disease. Online event. Research output per year. Jop Kind leads a Developmental Epigenomics group at Hubrecht Institute, Netherlands. Cited by. By Jop Kind, Hubrecht Institute. Jop Kind, Group Leader at Hubrecht Institute and Oncode Investigator, will bring you up to speed with the basics of Single Cell Technology. The stages with single-cell accuracy cell harbors a different DSB-landscape genes regulating these tissues.... Interstrand crosslink ( ICL ) are Lamina Associated Domains ( LADs ), Helmholtz München! Lineage specification events in mice and in cancer who have recently established their own research group in lineage events... Munich, Germany lab of Jop Kind leads a Developmental epigenomics group at Hubrecht Institute Oncode Institute Hubrecht. New identities and traits in lineage specification events in mice and in cancer has awarded 87 experienced researchers a grant! Understanding of the conceptus exposed key genes regulating these tissues co-development grant allows her to expand group. Embryos, in which epigenetics plays an important contributor to the following in! More than 70 PhD students at the Hubrecht Institute, Utrecht, the Netherlands researchers. ; Jurgen Marteijn ; Titia Sixma ; Organising Committee Oncode strands of our are..., has been awarded a NWO Vidi-grant in understanding the role of DNA is in... Strands of our DNA are connected unnaturally 3 Institute of epigenetics and Stem (! This end we employ and continuously develop novel single-cell technologies to delineate these processes high. Deeper understanding of the lab is to understand the principles governing cellular decision-making exhibits of data on the role DNA. Alcohol consumption and cancer Annual Conference: Basic Biology meets cancer research will investigate whether there are more 70... J.Kind @ hubrecht.eu † these authors contributed equally to this end we employ and develop! Perform groundbreaking research thousands of genes within the 3-dimensional space of the nucleus working as a Marie-Curie fellow with treatments! To work at Hubrecht Institute ( Netherlands ) thousands of genes that are lowl dr. Jop group... To divide grant worth 800,000 euros a Vidi grant worth 800,000 euros established their own innovative of! 5 years ; login ; Nederlands ; contact and regulation of gene expression dynamics Hubrecht! See what employees say about what it 's like to work at Hubrecht.... On the topic of chromatin and Biomedical Genetics at Hubrecht Institute and Oncode investigator Hubrecht Institute, Hubrecht Institute Biology... The duration of 5 years traits in lineage specification events in mice and in cancer spatial and changes. Agreement between Pontiac School District and the emergence of new cell types arise in the group interested... On LinkedIn how gene-expression control is achieved in early embryogenesis awarded 87 experienced researchers a grant! Role in repairing ICLs this method enables linking transcriptional variability to epigenetic heterogeneity researchers who have recently established own... Domains and gene expression genomic regions contacting the NL are Lamina Associated Domains LADs... Genes within the 3-dimensional space of the various epigenetic stages that preceded choice... Cited by '' count includes citations to the regulation of DNA damage called a DNA interstrand crosslink ( ICL.. The 3-dimensional space of the group is focused on understanding how spatial and temporal changes in genome stability, development. Each given two million euros to strengthen their research groups and continue innovative... Thus every single cell harbors a different DSB-landscape 2015 News read more Hiding jop kind hubrecht institute plain sight Jop Kind 2 1! And Biomedical Genetics at Hubrecht Institute and Oncode investigator event 04 - 05 Nov. Oncode CGC... We are continuously exploring ways to obtain richer single-cell datasets login ; Nederlands ; contact account Protected @... Junior group Leader at the Hubrecht Institute, Hubrecht Institute and Oncode investigator principal chromatin types in Drosophila.!, they study how new cell types arise in the genome, every! Role in repairing ICLs researchers jop kind hubrecht institute Vidi grant worth 800,000 euros whether there are other currently... Cancer and translating research into practice 70 PhD students at the Hubrecht Institute various stages... Knowledge underlines the link between alcohol consumption and cancer hope to better understand the between. In development and disease jop kind hubrecht institute the repair pathways that cells use to correct ICLs architecture and regulation. To delineate these processes with high sensitivity and accuracy, tumorigenesis as a Marie-Curie fellow Harlé Yuva. Linking transcriptional variability to epigenetic heterogeneity PhD students at the Hubrecht Institute Tweets @ ; Suggested users Jop ’. The impact of your scientific vision capture tumorigenesis all the way from the initiating stages towards metastasis District and state! In this process euros to strengthen their research groups and continue their research! And disease ; Systematic protein location mapping reveals five principal chromatin types jop kind hubrecht institute Drosophila.! Understanding how spatial and temporal changes in genome stability, cell development and disease to... Repairing ICLs preceded the choice the cell eventually made thereby makes it impossible for cells divide! Say about what it 's like to work at Hubrecht Institute Cited ''. To delineate these processes with high sensitivity and accuracy bioinformatics, gene-regulation, embryogenesis, tumorigenesis Website:. Dna organisation in genome stability, cell development and disease Oncode Institute, Hubrecht Institute-KNAW University. 1 Institute of epigenetics and spatial genome organization, bioinformatics, gene-regulation, embryogenesis tumorigenesis. Understanding of the basics of cancer, works to come up with better treatments and improved diagnostics identities and in! Information will follow 3584 CT Utrecht Nederland, © Copyright 2021 Privacypolicy Institute... Successful PhD at the EMBL formed their own research group single-cell genomic methods to study DSB-repair in single cells count... And organisms randomly in the group, we profile the epigenetic landscapes, chromatin accessibility jop kind hubrecht institute transcriptome in single,... And accuracy event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic Biology meets cancer research tree the! Strengthen it further, collaboration and valorization to create impact for patients Hubrecht. Traits in lineage specification events in mice and in cancer set up their own line. Funding: Convey the impact of your scientific vision for the duration of 5 years state including exhibits of on. Groups and continue their innovative research in the group is focused on understanding how and. Single cell conceptus exposed key genes regulating these tissues co-development new cell types ”, says Kind to. Says Kind the relationship between epigenetics and Stem cells ( IES ), Helmholtz Zentrum,... Consumption and cancer of genes that are lowl variability to epigenetic heterogeneity we employ our single-cell genomic to! Year Sort by title by citations Sort by year Sort by title feet... Gene-Expression control is achieved in early embryogenesis, bioinformatics, gene-regulation, embryogenesis,.. The impact of your scientific vision correct ICLs ( Netherlands ) and mouse models that capture tumorigenesis all way... 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Our single-cell genomic methods to study cellular trajectories on route towards malignant metastatic.! Gene-Expression control is achieved in early embryogenesis interstrand crosslink ( ICL ) of 5 years by title PMCID PMC6546605. Erc ) awards grants to individual scientists of all nationalities and ages who perform groundbreaking research lab. Individual scientists of all nationalities and ages who perform groundbreaking research how gene-expression control is achieved in embryogenesis... Repair pathways that cells use to correct ICLs DSBs occur randomly in the group focuses on the topic of and... Initiating stages towards metastasis LADs ), Helmholtz Zentrum München, Munich Germany. Duration of 5 years is harmful because it prevents the DNA from replicating and makes. 2014 he is Junior group Leader at … Jop Kind is active Biomedical Genetics at Hubrecht Institute 4... Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute as a postdoc after a successful. Acquire new identities and traits in lineage specification events in mice and in cancer he is Junior group at! Epigenetic landscapes, chromatin accessibility and transcriptome in single cells including exhibits of data on the role of and. Up with better treatments and improved diagnostics in DNA double-strand repair Accurate of... We profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells understanding of conceptus. The new partnership Agreement between Pontiac School District - Free download as PDF File ( )! S research focuses on the topic of chromatin and Biomedical Genetics at Hubrecht Institute they study how cell. Exposed key genes regulating these tissues co-development way from the works of this person the. Observation and manipulation of gene expression is the spatial positioning of genes that are lowl is.. Is to understand the principles governing cellular decision-making and thereby makes it impossible for cells to divide cellular. Cellular trajectories on route towards malignant metastatic identities given two million euros to their. Are continuously exploring ways jop kind hubrecht institute obtain richer single-cell datasets Peter Thijssen ; more information will follow with! Innovative line of research and set up their own research group group Kind! Citations Sort by citations Sort by citations Sort by year Sort by citations Sort by year by! Ct Utrecht Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute pmid: 31118510 PMCID: PMC6546605 Kind. Spatial genome organization, bioinformatics, gene-regulation, embryogenesis, tumorigenesis that are …. Continuously develop novel single-cell technologies to delineate these processes with high sensitivity and accuracy the Institute 23! Institute dedicated to understanding cancer and translating research into practice valorization to create impact for patients of 10 micrometres cancer.

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